Our group focuses on major areas of neuroscience:
Hereditary neuropathy
We aim to discover new treatments for inherited neurological disorders including X-linked dystonia-parkinsonism and DYT1 dystonia.
NEURO-ONCOLOGY
Our research is determined on finding new means to combat incurable brain cancers with immuno-gene therapy and other combination treatments.
BRAIN delivery vehicles
Our vision is to optimize existing and create new platforms to target payloads to the brain. We apply viral and non-viral methods such as AAV-mediated gene therapy and extracellular vesicle technology for multi-biomolecule transport.
BRAIN biomarkers
Our lab develops new diagnostic tools to monitor brain diseases. In that regard, brain-derived extracellular vesicle isolation from blood aids us to investigate disease-related biomarkers.
LATEST PUBLICATIONS
Explore our group’s featured publications below. For a complete list, click on the “More Publications” button.
Latest news
Read here our latest Breyne Lab updates!
If you have a question for our research team, please don’t hesitate to reach out.
Breyne Lab
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Molecular Neurogenetics Unit
Department of Neurology
Massachusetts General Hospital
Harvard Medical School
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149 13th Street, Boston, MA 02129